L3MBTL2 Polyklonaler Antikörper

L3MBTL2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24435-1-PBS

Synonyme

L(3)mbt-like protein 2, L(3)mbt like protein 2, l(3)mbt like 2 (Drosophila), H-l(3)mbt-like protein 2, H l(3)mbt like protein 2

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  WB analysis using 24435-1-AP (same clone as 24435-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24435-1-AP (L3MBTL2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24435-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

24435-1-PBS bindet in WB, Indirect ELISA L3MBTL2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: L3MBTL2 fusion protein Ag19571
• Vollständiger Name: l(3)mbt-like 2 (Drosophila)
• Berechnetes Molekulargewicht: 705 aa, 79 kDa
• Beobachtetes Molekulargewicht: 95-100 kDa
• GenBank-Zugangsnummer: BC017191
• Gene symbol: L3MBTL2
• Gene ID (NCBI): 83746
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

L3MBTL2 (Lethal (3) malignant brain tumor like 2) is a member of the MBT-domain proteins, which are involved in transcriptional repression and implicated in chromatin compaction. L3MBTL2 was most highly expressed in pachytene spermatocytes within the testis (PMID: 30760872).In addition, mutations in L3MBTL2 are prevalent in various cancers including leukemia, a disease characterized by alterations in multiple DNA repair proteins (PMID: 29581593).