• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

LAIR1 Rekombinanter Antikörper

LAIR1 Rekombinant Antikörper für IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241805C2

Kat-Nr. : 84677-4-PBS

Synonyme

241805C2, CD305, hLAIR1, LAIR 1, LAIR-1

Filter:
  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using LAIR1 Recombinant antibody (84677-4-RR)

    IHC staining of human tonsillitis using 84677-4-RR (same clone as 84677-4-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84677-4-RR (LAIR1 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84677-4-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using LAIR1 Recombinant antibody (84677-4-RR)

    IHC staining of human tonsillitis using 84677-4-RR (same clone as 84677-4-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84677-4-RR (LAIR1 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84677-4-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of THP-1 cells using LAIR1 Recombinant antibody (84677-4-RR)

    IF Staining of THP-1 using 84677-4-RR (same clone as 84677-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using LAIR1 antibody (84677-4-RR, Clone: 241805C2 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84677-4-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84677-4-PBS bindet in IHC, IF/ICC, Indirect ELISA LAIR1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen LAIR1 fusion protein Eg2329
Vollständiger Name leukocyte-associated immunoglobulin-like receptor 1
Berechnetes Molekulargewicht 287 aa, 31 kDa
GenBank-ZugangsnummerBC027899
Gene symbol LAIR1
Gene ID (NCBI) 3903
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) is a transmembrane glycoprotein with a single immunoglobulin-like domain and a cytoplasmic tail containing two immune receptor tyrosine-based inhibitory motifs (PMID: 9285412). LAIR1 is expressed on the majority of human PBMCs, including NK, T, B, monocytes, and dendritic cells, as well as the majority of thymocytes (PMID: 10229813). It functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of NK cells, B cells and T cells. LAIR1 is a collagen receptor (PMID: 16754721). Tumor-expressed collagens can modulate immune cell function through the inhibitory collagen receptor LAIR1 (PMID: 21955987).