LAMA4 (Isoform 3) Polyklonaler Antikörper

LAMA4 (Isoform 3) Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10465-1-PBS

Synonyme

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  WB analysis of human heart using 10465-1-AP (same clone as 10465-1-PBS)

  human heart tissue were subjected to SDS PAGE followed by western blot with 10465-1-AP (LAMA4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10465-1-PBS in a different storage buffer formulation.

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  WB analysis of human skeletal muscle using 10465-1-AP (same clone as 10465-1-PBS)

  human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 10465-1-AP (LAMA4 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10465-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary using 10465-1-AP (same clone as 10465-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 10465-1-AP (LAMA4 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 10465-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary using 10465-1-AP (same clone as 10465-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 10465-1-AP (LAMA4 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 10465-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

10465-1-PBS bindet in WB, IHC, Indirect ELISA LAMA4 (Isoform 3) und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: LAMA4 (Isoform 3) fusion protein Ag0736
• Vollständiger Name: laminin, alpha 4
• Berechnetes Molekulargewicht: 13 kDa
• Beobachtetes Molekulargewicht: 11-13 kDa
• GenBank-Zugangsnummer: BC004241
• Gene symbol: Laminin alpha 4/LAMA4
• Gene ID (NCBI): 3910
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Laminin is a basement membrane glycoprotein composed of three nonidentical chains, A, B1, and B2 (PMID: 7959779). LAMA4 (laminin, alpha 4), an A chain variant, is a subunit of laminin-8 (laminin-411), laminin-9 (laminin-421) and laminin-14 (laminin-423) (PMID: 10842354; 10964957). LAMA4 is widely distributed in developing and adult human tissues, and mainly localized to mesenchyme-derived tissues (PMID: 12133914). It may have a role in formation and function of endothelium, transmigration of inflammatory cells through endothelium, and invasion of certain tumors (PMID: 17533363). Three alternatively spliced mRNAs give rise to three isoforms. This antibody was generated against the full length (1-120aa) of isoform 3.

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