LAMC2 Polyklonaler Antikörper

LAMC2 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(10)

Rezensionen (1)

Kat-Nr. : 19698-1-AP

Synonyme

B2T, BM600, CSF, CSF 140 kDa subunit, EBR2, EBR2A, Epiligrin subunit gamma, Kalinin subunit gamma, Ladsin 140 kDa subunit, LAMB2T, LAMC2, Laminin 5 subunit gamma, Laminin B2t chain, Laminin subunit gamma 2, laminin, gamma 2, LAMNB2, Nicein subunit gamma

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  WB analysis of A431 using 19698-1-AP

  A431 cells were subjected to SDS PAGE followed by western blot with 19698-1-AP (LAMC2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: A431-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 10 publications below
• IHC: See 1 publications below
• IF: See 1 publications below

Produktinformation

19698-1-AP bindet in WB, IHC, IF, ELISA LAMC2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: laminin, gamma 2
• Berechnetes Molekulargewicht: 131 kDa
• Beobachtetes Molekulargewicht: 140 kDa
• GenBank-Zugangsnummer: NM_005562
• Gene symbol: LAMC2
• Gene ID (NCBI): 3918
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LAMC2, also named as LAMB2T and LAMNB2, is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. LAMC2 binds to cells via a high affinity receptor. Laminin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells.

Publikationen

Species	Application	Title
rat	WB	J Proteomics; Proteomic analysis reveals the protective effects of emodin on severe acute pancreatitis induced lung injury by inhibiting neutrophil proteases activity.; Authors - Caiming Xu
human	WB	Mol Med Rep; Laminin‑332 mediates proliferation, apoptosis, invasion, migration and epithelial‑to‑mesenchymal transition in pancreatic ductal adenocarcinoma.; Authors - Caiqun Huang
Mouse	WB	Int J Mol Med; The Notch pathway mediates the angiotensin II-induced synthesis of extracellular matrix components in podocytes.; Authors - Min Yao
human	WB	Cancer Res; A Genome-Wide Synthetic Lethal Screen Identifies Spermidine Synthase as a Target to Enhance Erdafitinib Efficacy in FGFR-Mutant Bladder Cancer; Authors - Yanchao Yu
human	WB,IHC	Sci Transl Med; Connexins orchestrate progression of breast cancer metastasis to the brain by promoting FAK activation; Authors - Girieca Lorusso
human	WB,IF	J Transl Med; Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction; Authors - Jing Feng

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.

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FH

Guorong (Verified Customer) (11-22-2022)

Clear band

• Applications: Western Blot
• Primary Antibody Dilution: 1:1000
• Cell Tissue Type: ARPE-19

LAMC2 Antibody Western Blot validation (1:1000 dilution) in ARPE-19 (Cat no:19698-1-AP)