LAPTM4B Monoklonaler Antikörper

LAPTM4B Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

2A11H6

Kat-Nr. : 68981-3-Ig

Synonyme

2A11H6, LAPTM4beta, Lysosomal-associated transmembrane protein 4B, Lysosome-associated transmembrane protein 4-beta, PSEC0001

---

• 

  WB analysis using 68981-3-Ig

  Various lysates were subjected to SDS PAGE followed by western blot with 68981-3-Ig (LAPTM4B antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

• 

  Affinity and Kinetic Characterization of 68981-3-Ig

  Biolayer interferometry (BLl) kinetic assays of 68706-1-Ig against Human MMP1 were performed. The affinity constant is below 19.9 nM.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: TT cells, K-562-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

68981-3-Ig bindet in WB, ELISA LAPTM4B und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: LAPTM4B fusion protein Ag38696
• Vollständiger Name: lysosomal protein transmembrane 4 beta
• Berechnetes Molekulargewicht: 41 kDa
• Beobachtetes Molekulargewicht: 35 kDa
• GenBank-Zugangsnummer: BC014129
• Gene symbol: LAPTM4B
• Gene ID (NCBI): 55353
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LAPTM4B, a novel oncoprotein, is associated with the prognosis of cancer, and may play important roles in the initiation, promotion and metastasis of tumors. It was initially identified as a hepatocellular carcinoma-associated gene, and was recently shown to be up-regulated in various human cancers. Some studies indicated that LAPTM4B may be an useful marker of prognosis in ovarian carcinoma and endometrial cancer. LAPTM4B belongs to the LAPTM4/LAPTM5 transporter family. It has 3 isoforms with molecular masses 41 kDa, 35 kDa and 24 kDa.