LARP7 Polyklonaler Antikörper

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• KD/KO Validated

LARP7 Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17067-1-PBS

Synonyme

HDCMA18P, hLARP7, La related protein 7, La-related protein 7, PIP7S

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  WB analysis using 17067-1-AP (same clone as 17067-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17067-1-AP (LARP7 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  WB analysis of human brain using 17067-1-AP (same clone as 17067-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 17067-1-AP (LARP7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 17067-1-AP (LARP7 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 17067-1-AP (LARP7 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 17067-1-AP (LARP7 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human spleen using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human spleen using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 17067-1-AP (LARP7 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HeLa using 17067-1-AP (same clone as 17067-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HeLa cells using LARP7 antibody (17067-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

17067-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA LARP7 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: LARP7 fusion protein Ag10891
• Vollständiger Name: La ribonucleoprotein domain family, member 7
• Berechnetes Molekulargewicht: 582 aa, 67 kDa
• Beobachtetes Molekulargewicht: 67 kDa
• GenBank-Zugangsnummer: BC006981
• Gene symbol: LARP7
• Gene ID (NCBI): 51574
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LARP7 belongs to the LARP RNA-binding protein family, which includes the lupus LA antigen gene, and modulates the metabolism and function of a variety of RNA species [PMID:20138158]. LARP7 binds to the 7SK RNP complex, and sequesters the positive transcription elongation factor b (P-TEFb) in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. binds to and stabilizes 7sk snRNA[PMID:19416841].