LGALS13 Polyklonaler Antikörper
LGALS13 Polyklonal Antikörper für WB, IHC, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, IHC, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 17823-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
17823-1-PBS bindet in WB, IHC, Indirect ELISA LGALS13 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | LGALS13 fusion protein Ag12192 |
| Vollständiger Name | lectin, galactoside-binding, soluble, 13 |
| Berechnetes Molekulargewicht | 139 aa, 16 kDa |
| Beobachtetes Molekulargewicht | 16 kDa |
| GenBank-Zugangsnummer | BC066304 |
| Gene symbol | LGALS13 |
| Gene ID (NCBI) | 29124 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Galectins are glycan-binding proteins that regulate innate and adaptive immune responses, and some confer maternal-fetal immune tolerance in eutherian mammals. Three of the five human cluster galectins are solely expressed in the placenta, where they may confer additional immunoregulatory functions to enable deep placentation (PMID: 25191322). One of these is galactoside-binding soluble lectin 13 (LGALS13, also known as Galectin-13 and PP13), which has a high affinity for the sugar residues of glycoproteins. PP13 is implicated in placentation and is involved in inflammation and immune defense required for trophoblast invasion during uterine artery remodeling in early pregnancy (PMID: 19497882; 10527825; 21596368; 26018511).



