LGALS13 Polyklonaler Antikörper

LGALS13 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17823-1-PBS

Synonyme

Galectin-13, Gal 13, GAL13, Gal-13, Galactoside-binding soluble lectin 13



Geprüfte Anwendungen

Produktinformation

17823-1-PBS bindet in WB, IHC, Indirect ELISA LGALS13 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen LGALS13 fusion protein Ag12192
Vollständiger Name lectin, galactoside-binding, soluble, 13
Berechnetes Molekulargewicht 139 aa, 16 kDa
Beobachtetes Molekulargewicht16 kDa
GenBank-ZugangsnummerBC066304
Gene symbol LGALS13
Gene ID (NCBI) 29124
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Galectins are glycan-binding proteins that regulate innate and adaptive immune responses, and some confer maternal-fetal immune tolerance in eutherian mammals.  Three of the five human cluster galectins are solely expressed in the placenta, where they may confer additional immunoregulatory functions to enable deep placentation (PMID: 25191322). One of these is galactoside-binding soluble lectin 13 (LGALS13, also known as Galectin-13 and PP13), which has a high affinity for the sugar residues of glycoproteins. PP13 is implicated in placentation and is involved in inflammation and immune defense required for trophoblast invasion during uterine artery remodeling in early pregnancy (PMID: 19497882; 10527825; 21596368; 26018511).