LGALS3BP Monoklonaler Antikörper
LGALS3BP Monoklonal Antikörper für ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human
Anwendung
ELISA
Konjugation
Unkonjugiert
CloneNo.
3G4F11
Kat-Nr. : 60066-2-Ig
Synonyme
Galerie der Validierungsdaten
Geprüfte Anwendungen
Empfohlene Verdünnung
| Anwendung | Verdünnung |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Produktinformation
60066-2-Ig bindet in ELISA LGALS3BP und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Maus / IgG1 |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | LGALS3BP fusion protein Ag0294 |
| Vollständiger Name | lectin, galactoside-binding, soluble, 3 binding protein |
| Berechnetes Molekulargewicht | 585 aa, 65 kDa |
| Beobachtetes Molekulargewicht | 90 kDa |
| GenBank-Zugangsnummer | BC002403 |
| Gene symbol | LGALS3BP |
| Gene ID (NCBI) | 3959 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Caprylsäure/Ammoniumsulfat-Präzipitation |
| Lagerungspuffer | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. |
| Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP is a widely expressed, secreted galectin. It has been found elevated in the serum of patients with various types of breast, lung, colorectal, ovary, and endometrial cancer, and in those infected by the human immunodeficiency virus (HIV). High expression levels of LGALS3BP are associated with a shorter survival, the occurrence of metastasis or a reduced response to chemotherapy. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Immunoblotting showed that LGALS3BP is likely contained in breast milk, serum, semen, saliva, urine, and tears.
