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LGALS9/Galectin-9 Polyklonaler Antikörper

LGALS9/Galectin-9 Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17938-1-PBS

Synonyme

Galectin 9, LGALS9, Ecalectin, Gal 9, Gal-9

Filter:
  • Western Blot (WB) analysis of various lysates using LGALS9/Galectin-9 Polyclonal antibody (17938-1-AP)

    WB analysis using 17938-1-AP (same clone as 17938-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17938-1-AP (LGALS9/Galectin-9 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17938-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human ovary cancer tissue using LGALS9/Galectin-9 Polyclonal antibody (17938-1-AP)

    IHC staining of human ovary cancer using 17938-1-AP (same clone as 17938-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 17938-1-AP (Galectin-9 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17938-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U-937 cells using LGALS9/Galectin-9 Polyclonal antibody (17938-1-AP)

    IF Staining of U-937 using 17938-1-AP (same clone as 17938-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U-937 cells using LGALS9/Galectin-9 antibody (17938-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 17938-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17938-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA LGALS9/Galectin-9 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen LGALS9/Galectin-9 fusion protein Ag12209
Vollständiger Name lectin, galactoside-binding, soluble, 9
Berechnetes Molekulargewicht 323 aa, 36 kDa
Beobachtetes Molekulargewicht34-40 kDa
GenBank-ZugangsnummerBC110340
Gene symbol Galectin-9
Gene ID (NCBI) 3965
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The galectins, formerly known as S-type lectins, are a family of β-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-9 (LGALS9) is a tandem repeat-type member of the galectin family. It has three isoforms (named galectin-9L, galectin-9M, and galectin-9S): long type of 355 amino acids, medium type of 323 amino acids, and short type of 311 amino acids. Galectin-9 is ubiquitously expressed in a variety of tissues, including lymph nodes and spleen, and overexpressed in Hodgkin disease tissue. It is involved in chemoattraction, apoptosis, and the regulation of cell differentiation and has anti-allergic effects. It has been reported that galectin-9 is a ligand for Tim-3, through which galectin-9 can induce T-helper type 1 lymphocyte (Th1) death.