LGR4 Polyklonaler Antikörper
LGR4 Polyklonal Antikörper für IHC, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
IHC, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 20150-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
20150-1-PBS bindet in IHC, Indirect ELISA LGR4 und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | LGR4 fusion protein Ag13695 |
| Vollständiger Name | leucine-rich repeat-containing G protein-coupled receptor 4 |
| Berechnetes Molekulargewicht | 104 kDa |
| GenBank-Zugangsnummer | BC033039 |
| Gene symbol | LGR4 |
| Gene ID (NCBI) | 55366 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
LGR4, also known as GPR48, is a membrane of the leucine-rich GPCR family. LGR4 is composed of a large NH2-terminal extracellular domain containing 18 LRRs, the seven membrane-spanning segments, and a COOH-terminal intracellular domain. LGR4 is a receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. It has also been shown that LGR4 regulates cyclic AMP/protein kinase A (PKA) signalling. (PMID: 23756652; 17178856; 24212090)







