LGR5 Polyklonaler Antikörper
LGR5 Polyklonal Antikörper für WB, ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IHC, IF, ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 30007-1-AP
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in WB | BGC-823-Zellen, HEK-293-Zellen, Maushirngewebe, Rattenhirngewebe, SGC-7901-Zellen, SKOV-3-Zellen |
Empfohlene Verdünnung
Anwendung | Verdünnung |
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Western Blot (WB) | WB : 1:500-1:2000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Veröffentlichte Anwendungen
IHC | See 1 publications below |
IF | See 3 publications below |
Produktinformation
30007-1-AP bindet in WB, IHC, IF, ELISA LGR5 und zeigt Reaktivität mit human, Maus, Ratten
Getestete Reaktivität | human, Maus, Ratte |
In Publikationen genannte Reaktivität | Maus |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Polyklonal |
Typ | Antikörper |
Immunogen | LGR5 fusion protein Ag31625 |
Vollständiger Name | leucine-rich repeat-containing G protein-coupled receptor 5 |
Berechnetes Molekulargewicht | 907 aa, 100 kDa |
Beobachtetes Molekulargewicht | 100 kDa |
GenBank-Zugangsnummer | BC096324 |
Gene symbol | LGR5 |
Gene ID (NCBI) | 8549 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Antigen-Affinitätsreinigung |
Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol |
Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) also known as G-protein coupled receptor 49 (GPR49) or G-protein coupled receptor 67 (GPR67) is a protein that in humans is encoded by the LGR5 gene. It is a member of GPCR class A receptor proteins. R-spondin proteins are the biological ligands of LGR5. LGR5 is expressed across a diverse range of tissue such as in the muscle, placenta, spinal cord and brain and particularly as a biomarker of adult stem cells in certain tissues.LGR5 is crucial during embryogenesis as LGR null studies in mice incurred 100% neonatal mortality accompanied by several craniofacial distortions such as ankyloglossia and gastrointestinal dilation (PMID: 9642114, 16575208, 525477).
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
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WB protocol for LGR5 antibody 30007-1-AP | Protokoll herunterladen |
STANDARD-PROTOKOLLE | |
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Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |
Publikationen
Species | Application | Title |
---|---|---|
Burns Trauma Nocardia rubra cell-wall skeleton mitigates whole abdominal irradiation-induced intestinal injury via regulating macrophage function | ||
Acta Histochem Stimulation of mouse hair regrowth by exosomes derived from human umbilical cord mesenchymal stem cells | ||
Zool Res Peptide Cy RL-QN15 accelerates hair regeneration in diabetic mice by binding to the Frizzled-7 receptor | ||
Int J Biol Macromol Integrated bulk and single-cell RNA sequencing unveils the temporal and spatial dynamics of epidermal cell adhesion |