LHX2 Polyklonaler Antikörper

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• KD/KO Validated

LHX2 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 18133-1-AP

Synonyme

hLhx2, Homeobox protein LH 2, LH2, LHX2, LIM homeobox 2, LIM homeobox protein 2, LIM/homeobox protein Lhx2

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Galerie der Validierungsdaten

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  WB analysis of Jurkat using 18133-1-AP

  WB result of LHX2 antibody (18133-1-AP; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-LHX2 transfected Jurkat cells.

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  WB analysis using 18133-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 18133-1-AP (LHX2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: A549-Zellen, Daudi-Zellen, Jurkat-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

18133-1-AP bindet in WB, ELISA LHX2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: LHX2 fusion protein Ag12717
• Vollständiger Name: LIM homeobox 2
• Berechnetes Molekulargewicht: 406 aa, 44 kDa
• Beobachtetes Molekulargewicht: 50-55 kDa
• GenBank-Zugangsnummer: BC093662
• Gene symbol: LHX2
• Gene ID (NCBI): 9355
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LHX proteins can activate or repress gene transcription by direct DNA binding and association with co-activators or co-repressors through their LIM domain. The LIM homeobox 2 (LHX2), also known as LH2, is a member of the LIM homeodomain family of proteins. LHX2 functions as a nuclear transcription co-factor and is reported to be involved in many important physiological processes, such as cell division, cell proliferation, specific cell-type differentiation, and cerebral cortex development. LHX2 promotes the growth and metastasis of nasopharyngeal carcinoma by regulating Wnt signaling and plays a vital role in breast cancer's progression and prognosis(PMID: 37345110).