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LILRB2/CD85d Polyklonaler Antikörper

LILRB2/CD85d Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14154-1-PBS

Synonyme

LILRB2, CD85 antigen-like family member D, CD85d, ILT 4, ILT4

Filter:
  • Western Blot (WB) analysis of various lysates using LILRB2/CD85d Polyclonal antibody (14154-1-AP)

    WB analysis using 14154-1-AP (same clone as 14154-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14154-1-AP (LILRB2/CD85d antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14154-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of THP-1 cells using LILRB2/CD85d Polyclonal antibody (14154-1-AP)

    IF Staining of THP-1 using 14154-1-AP (same clone as 14154-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using LILRB2/CD85d antibody (14154-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 14154-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

14154-1-PBS bindet in WB, IF/ICC, Indirect ELISA LILRB2/CD85d und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen LILRB2/CD85d fusion protein Ag5336
Vollständiger Name leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
Berechnetes Molekulargewicht 598 aa, 65 kDa
Beobachtetes Molekulargewicht60-65 kDa
GenBank-ZugangsnummerBC036827
Gene symbol LILRB2
Gene ID (NCBI) 10288
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LILRB2 (Leukocyte immunoglobulin-like receptor subfamily B member 2), also known as ILT4, CD85d or MIR10, is a type I transmembrane glycoprotein that contains four extracellular immunoglobulin domains, a transmembrane domain, and three cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) (PMID: 33928233). LILRB2 is mainly expressed in immunocytes including monocytes, macrophages, and dendritic cells, and transduces negative signals by its association with SHP-1 phosphatase via the ITIMs (PMID: 35717259). LILRB2 can interact with various ligands such as HLA-A, HLA-B, HLA-C, HLA-G, HLA-F, CD1c, CD1d, angiopoietin-like proteins (ANGPTLs), and SEMA4A.