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LNX1 Polyklonaler Antikörper

LNX1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13124-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse testis tissue using LNX1 Polyclonal antibody (13124-1-AP)

    WB analysis of mouse testis using 13124-1-AP (same clone as 13124-1-PBS)

    mouse testis tissue were subjected to SDS PAGE followed by western blot with 13124-1-AP (LNX1 antibody) at dilution of 1:70 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13124-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse kidney tissue using LNX1 Polyclonal antibody (13124-1-AP)

    WB analysis of mouse kidney using 13124-1-AP (same clone as 13124-1-PBS)

    mouse kidney tissue were subjected to SDS PAGE followed by western blot with 13124-1-AP (LNX1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13124-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

13124-1-PBS bindet in WB, Indirect ELISA LNX1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen LNX1 fusion protein Ag3823
Vollständiger Name ligand of numb-protein X 1
Berechnetes Molekulargewicht 728 aa, 81 kDa
Beobachtetes Molekulargewicht 70 kDa
GenBank-ZugangsnummerBC022983
Gene symbol LNX1
Gene ID (NCBI) 84708
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LNX1 (Ligand of Numb, protein X 1) was originally identified as a binding partner of the cell-fate determinant Numb and was reported to be involved in ubiquitylation and degradation of Numb. LNX1 contains four PDZ domains and may function as a scaffold for a multi-protein complex. LNX1 has two splicing variants, LNX1p70 and LNX1p80. LNX1p70 has the N-terminal Numb binding region and four PDZ domains, whereas LNX1p80 has an additional RING-finger domain at the N-terminus followed by a Numb-binding region and four PDZ domains. This antibody can detect both LNX1p70 and LNX1p80, around 70-80 kDa and 80-100 kDa, respectively.