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LONP1 Monoklonaler Antikörper
LONP1 Monoklonal Antikörper für WB, IHC, IF/ICC, Cytometric bead array, Indirect ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IHC, IF/ICC, Cytometric bead array, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
1C6C12
Kat-Nr. : 66043-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66043-1-PBS bindet in WB, IHC, IF/ICC, Cytometric bead array, Indirect ELISA LONP1 und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte | 
| Wirt / Isotyp | Maus / IgG1 | 
| Klonalität | Monoklonal | 
| Typ | Antikörper | 
| Immunogen | LONP1 fusion protein Ag7306 | 
| Vollständiger Name | lon peptidase 1, mitochondrial | 
| Berechnetes Molekulargewicht | 106 kDa | 
| Beobachtetes Molekulargewicht | 100 kDa | 
| GenBank-Zugangsnummer | BC000235 | 
| Gene symbol | LONP1 | 
| Gene ID (NCBI) | 9361 | 
| Konjugation | Unkonjugiert | 
| Form | Liquid | 
| Reinigungsmethode | Protein-G-Reinigung | 
| Lagerungspuffer | PBS only | 
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. | 
Hintergrundinformationen
LONP1(Lon protease homolog, mitochondrial) is also named as LONP, LONHS, HLON, LON, PRSS15, PIM1, MGC1498 and belongs to the peptidase S16 family. It seems to play a major role in the elimination of oxidatively modified proteins in the mitochondrial matrix(PMID:18021745). LONP1, also a nuclearly encoded and mitochondrially located stress-responsive protease, is involved in heme-mediated ALAS-1 turnover(PMID:21659532). It recognizes specific surface determinants or folds, initiates proteolysis at solvent-accessible sites, and generates unfolded polypeptides that are then processively degraded(PMID:15870080).





































