LONP2 Rekombinanter Antikörper

LONP2 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

251061E10

Kat-Nr. : 86291-2-RR

Synonyme

EC:3.4.21.53, Lon protease 2, Lon protease homolog 2, peroxisomal, Lon protease-like protein 2, LONP

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  WB analysis using 86291-2-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 86291-2-RR (LONP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 86291-2-RR

  Biolayer interferometry (BLl) kinetic assays of 86291-2-RR against Human LONP2 were performed. The affinity constant is 0.636 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Jurkat-Zellen, HUVEC-Zellen, K-562-Zellen, Mausnierengewebe, SH-SY5Y-Zellen, U2OS-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

86291-2-RR bindet in WB, ELISA LONP2 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: LONP2 fusion protein Ag12650
• Vollständiger Name: lon peptidase 2, peroxisomal
• Berechnetes Molekulargewicht: 852 aa, 95 kDa
• Beobachtetes Molekulargewicht: 95 kDa
• GenBank-Zugangsnummer: BC093910
• Gene symbol: LONP2
• Gene ID (NCBI): 83752
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LONP2 (Lon Peptidase 2, Peroxisomal) is an important ATP-dependent protease. It is primarily located in peroxisomes and is responsible for maintaining the proteostasis of this organelle. By degrading misfolded proteins and selectively regulating metabolic enzymes, LONP2 plays a central role in maintaining peroxisomal proteostasis and metabolic balance. Dysfunction of LONP2 is closely related to a variety of human diseases, including peroxisomal disorders, cancer, and neurodegenerative diseases.