LPPR5 Polyklonaler Antikörper

LPPR5 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 18842-1-PBS

Synonyme

PAP2D, Lipid phosphate phosphatase-related protein type 5, PAP2, Phosphatidic acid phosphatase type 2d, Phospholipid phosphatase-related protein type 5

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  IHC staining of mouse brain using 18842-1-AP (same clone as 18842-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 18842-1-AP (LPPR5 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18842-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 18842-1-AP (same clone as 18842-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 18842-1-AP (LPPR5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18842-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

18842-1-PBS bindet in IHC, Indirect ELISA LPPR5 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: phosphatidic acid phosphatase type 2
• Berechnetes Molekulargewicht: 35 kDa
• GenBank-Zugangsnummer: NM_001010861
• Gene symbol: PAP2D
• Gene ID (NCBI): 163404
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The lipid phosphate phosphatase-related proteins (LPPRs), also known as plasticity-related genes (PRGs), are a family of six transmembrane proteins that are enriched in brain. To date, five members have been identified (LPPR1-LPPR5). LPPR5 is an integral membrane protein linked to neuronal plasticity, which impedes NogoA- and LPA-mediated RhoA kinase signaling. LPPR5 modulates the Rho-GTPase pathway involved in cancer growth, vascularization, and the adaptive response to changes in the microenvironment. LPPR5 is pivotal in influencing growth, angiogenesis, and therapeutic resistance. (PMID: 26183180, PMID: 35328529)