LRP1 Monoklonaler Antikörper

LRP1 Monoklonal Antikörper für FC

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

5A6

Kat-Nr. : 65233-1-Ig

Synonyme

A2MR, Alpha 2 macroglobulin receptor, APOER, Apolipoprotein E receptor, APR, CD91, FLJ16451, IGFBP3R, LRP, LRP 1, LRP1, LRPICD, TGFBR5

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  FC experiment of U-87 MG using 65233-1-Ig

  1X10^6 U-87 MG cells were surface stained with 1 ug Anti-Human LRP1 (65233-1-Ig, Clone:5A6) and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) at dilution 1:1000 (red), or 1 ug Control Antibody. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: U-87 MG-Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

65233-1-Ig bindet in FC LRP1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Full length native protein (purified)
• Vollständiger Name: low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
• Berechnetes Molekulargewicht: 505 kDa
• GenBank-Zugangsnummer: BC045107
• Gene symbol: LRP1
• Gene ID (NCBI): 4035
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Stable for one year after shipment.

Hintergrundinformationen

LRP1 (Prolow-density lipoprotein receptor-related protein 1), also known as A2MR, APOER and CD91, is a type I transmembrane protein that belongs to the LDLR family. LRP1 is synthesized as a transmembrane glycosylated precursor of 600 kDa, and is subsequently cleaved to generate a large 515-kDa N-terminal extracellular subunit and an 85-kDa C-terminal transmembrane subunit, which are noncovalently associated with one another (PMID: 2112085; 8546712). LRP1 is a multifunctional receptor involved in the clearance of a large number of diverse ligands and modulating various cellular processes. LRP1 is implicated in conditions such as atherosclerosis, cancer and neurodegenerative diseases (PMID: 28381441).