LRP2-Specific Polyklonaler Antikörper

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• KD/KO Validated

LRP2-Specific Polyklonal Antikörper für WB, IHC, IF-P, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, IF-P, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 19700-1-PBS

Synonyme

LRP2, LRP 2, Low-density lipoprotein receptor-related protein 2, gp330, Glycoprotein 330

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  WB analysis using 19700-1-AP (same clone as 19700-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 19700-1-AP (LRP2-Specific antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19700-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 19700-1-AP (same clone as 19700-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 19700-1-AP (LRP2-Specific antibody) at dilution of 1:8000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19700-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 19700-1-AP (same clone as 19700-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 19700-1-AP (LRP2-Specific antibody) at dilution of 1:8000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19700-1-PBS in a different storage buffer formulation.

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  IF Staining of human kidney using 19700-1-AP (same clone as 19700-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human kidney tissue using LRP2-Specific antibody (19700-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 19700-1-PBS in a different storage buffer formulation.

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  IF Staining of human kidney using 19700-1-AP (same clone as 19700-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human kidney tissue using LRP2-Specific antibody (19700-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 19700-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

19700-1-PBS bindet in WB, IHC, IF-P, Indirect ELISA LRP2-Specific und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: low density lipoprotein-related protein 2
• Berechnetes Molekulargewicht: 522 kDa
• Beobachtetes Molekulargewicht: 522 kDa
• GenBank-Zugangsnummer: NM_004525
• Gene symbol: LRP2
• Gene ID (NCBI): 4036
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LRP2, also named as gp330 and Megalin, belongs to the LDLR family. It acts together with cubilin to mediate HDL endocytosis. LRP2 may participate in regulation of parathyroid hormone and para-thyroid-hormone-related protein release. Defects in LRP2 are the cause of Donnai-Barrow syndrome (DBS).