LSAMP Polyklonaler Antikörper

LSAMP Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13600-1-AP

Synonyme

IgLON family member 3, IGLON3, LAMP, LSAMP

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  WB analysis of human brain using 13600-1-AP

  human brain tissue were subjected to SDS PAGE followed by western blot with 13600-1-AP (LSAMP antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse brain using 13600-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 13600-1-AP (LSAMP antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: humanes Hirngewebe, Maushirngewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

13600-1-AP bindet in WB, ELISA LSAMP und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: LSAMP fusion protein Ag4542
• Vollständiger Name: limbic system-associated membrane protein
• Berechnetes Molekulargewicht: 338 aa, 37 kDa
• Beobachtetes Molekulargewicht: 64-68 kDa
• GenBank-Zugangsnummer: BC033803
• Gene symbol: LSAMP
• Gene ID (NCBI): 4045
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LSAMP, also known as LAMP, is a 64-68 kDa heavily glycosylated neural cell adhesion molecule expressed on the neuronal dendrites and somata (PMID: 1688937; 8666243). LSAMP is a member of the IgLON family. The amino acid sequence of LSAMP is highly conserved among species. Human LSAMP shares 99% amino acid sequence identity with rodent LSAMP. The impact of LSAMP protein on neurite outgrowth and neuronal connectivity has been established in a wide spectrum of psychiatric disorders in humans (PMID: 26136648). In mice, lack of LSAMP protein seemingly leads to a deterioration in the ability to adapt to novel stressful environments and stimuli (PMID: 22155487).