LTBP1 Rekombinanter Antikörper

LTBP1 Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250127A9

Kat-Nr. : 85820-1-PBS

Synonyme

Latent-transforming growth factor beta-binding protein 1, LTBP 1, TGF beta1 BP 1, TGF-beta1-BP-1, Transforming growth factor beta-1-binding protein 1

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  WB analysis using 85820-1-RR (same clone as 85820-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85820-1-RR (LTBP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85820-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP02129-1

  Cytometric bead array standard curve of MP02129-1, LTBP1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 85820-1-PBS. Detection antibody: 85820-3-PBS. Standard: Ag25392. Range: 0.313-40 ng/mL.

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  Cytometric bead array standard curve of MP02129-2

  Cytometric bead array standard curve of MP02129-2, LTBP1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 85820-2-PBS. Detection antibody: 85820-1-PBS. Standard: Ag25392. Range: 0.625-40 ng/mL.

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  Affinity and Kinetic Characterization of 85820-1-RR

  Biolayer interferometry (BLl) kinetic assays of 85820-1-RR against Human LTBP1 were performed. The affinity constant is 9.63 nM.

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Geprüfte Anwendungen

Produktinformation

85820-1-PBS bindet in WB, Cytometric bead array, Indirect ELISA LTBP1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: LTBP1 fusion protein Ag25392
• Vollständiger Name: latent transforming growth factor beta binding protein 1
• Berechnetes Molekulargewicht: 1721 aa, 187 kDa
• Beobachtetes Molekulargewicht: 150 kDa
• GenBank-Zugangsnummer: BC130289
• Gene symbol: LTBP1
• Gene ID (NCBI): 4052
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Latent Transforming Growth Factor Beta Binding Protein 1 (LTBP1) is a large extracellular matrix protein that belongs to the latent TGF-beta binding protein family. It plays a crucial role in the regulation of TGF-beta, a multifunctional cytokine involved in various cellular processes such as cell growth, differentiation, and immune response. LTBP1 is essential for TGF-beta folding, secretion, matrix localization, and activation. It forms latent complexes with TGF-beta by covalently binding the TGF-beta propeptide (LAP) via disulfide bonds in the endoplasmic reticulum. This complex is then secreted and targeted to the extracellular matrix, where TGF-beta can be activated by various mechanism