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LYPD6B Polyklonaler Antikörper

LYPD6B Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25508-1-PBS

Synonyme

CT116, Ly6/PLAUR domain-containing protein 6B, LYPD7

Filter:
  • Immunohistochemistry (IHC) staining of mouse lung tissue using LYPD6B Polyclonal antibody (25508-1-AP)

    IHC staining of mouse lung using 25508-1-AP (same clone as 25508-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 25508-1-AP (LYPD6B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25508-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse lung tissue using LYPD6B Polyclonal antibody (25508-1-AP)

    IHC staining of mouse lung using 25508-1-AP (same clone as 25508-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 25508-1-AP (LYPD6B antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25508-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25508-1-PBS bindet in IHC, Indirect ELISA LYPD6B und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen LYPD6B fusion protein Ag22008
Vollständiger Name LY6/PLAUR domain containing 6B
Berechnetes Molekulargewicht 183 aa, 20 kDa
GenBank-ZugangsnummerBC040176
Gene symbol LYPD6B
Gene ID (NCBI) 130576
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LYPD6B (containing the Ly6/PLAUR domain protein 6B), also known as LYPD7, is a member of the Ly6/uPAR superfamily of proteins. These proteins typically exhibit membrane-anchoring properties and participate in critical cellular signaling and adhesion processes. It is predominantly expressed in the central nervous system. LYPD6B functions as a key regulatory subunit that interacts with and modulates nicotinic acetylcholine receptors (nAChRs), specifically influencing their maturation, stability, and functional properties at synapses. This interaction is crucial for normal cholinergic signaling, which underpins cognitive functions such as learning and memory. Dysfunction of the LYPD6B is associated with multiple neurological disorders. (PMID: 23186997, PMID: 34631692, PMID: 39433742)