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Lamin B2 Monoklonaler Antikörper

Lamin B2 Monoklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2C7B1

Kat-Nr. : 68475-1-PBS

Synonyme

LMNB2, LMN2, Lamin-B2, LAMB2, 2C7B1

Filter:
  • Western Blot (WB) analysis of various lysates using Lamin B2 Monoclonal antibody (68475-1-Ig)

    WB analysis using 68475-1-Ig (same clone as 68475-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68475-1-Ig (Lamin B2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68475-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using Lamin B2 Monoclonal antibody (68475-1-Ig)

    IF Staining of HepG2 using 68475-1-Ig (same clone as 68475-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using Lamin B2 antibody (68475-1-Ig, Clone: 2C7B1 ) at dilution of 1:1000 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1), CL594-phalloidin (red). This data was developed using the same antibody clone with 68475-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68475-1-PBS bindet in WB, IF/ICC, Indirect ELISA Lamin B2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen Lamin B2 fusion protein Ag33296
Vollständiger Name lamin B2
Berechnetes Molekulargewicht 68 kDa
Beobachtetes Molekulargewicht 68 kDa
GenBank-ZugangsnummerBC006551
Gene symbol Lamin B2
Gene ID (NCBI) 84823
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Lamins are nuclear membrane structural components that are important in structural integrity of the nucleus and may also interact with chromatin (PMID: 33033404). Research studies show that lamin B2 knockout mice exhibit neuronal developmental defects and that both proteins are essential for typical brain development (PMID: 20145110). Mutations in Lamin B2 can result in a susceptibility to developing acquired partial lipodystrophy, a rare disorder characterized by the progressive loss of subcutaneous fat in a bilaterally symmetrical fashion (PMID: 16826530).