Ly-6C Rekombinanter Antikörper

Ly-6C Rekombinant Antikörper für FC

Wirt / Isotyp

Ratte / IgG2a

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

HK1.4

Kat-Nr. : 65669-1-PBS

Synonyme

Ly6c, Ly 6C, Ly6c1

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  FC experiment of mouse bone marrow cells using 65669-1-TR (same clone as 65669-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.5 ug Anti-Mouse Ly-6C (HK1.4) Rat IgG2a RecAb (65669-1-TR, Clone: HK1.4) or Rat IgG2a Isotype Control Recombinant Antibody (98427-1-TR, Clone: 250862A1), and FITC anti-Rat IgG2a antibody. Cells were then stained with APC Anti-Mouse CD11b (M1/70) (APC-65055, Clone: M1/70). Cells were not fixed. This data was developed using the same antibody clone with 65669-1-PBS in a different storage buffer formulation.

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  FC experiment of mouse bone marrow cells using 65669-1-TR (same clone as 65669-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.5 ug Anti-Mouse Ly-6C (HK1.4) Rat IgG2a RecAb (65669-1-TR, Clone: HK1.4) (red) or Rat IgG2a Isotype Control Recombinant Antibody (98427-1-TR, Clone: 250862A1) (blue), and FITC anti-Rat IgG2a antibody. Cells were not fixed. This data was developed using the same antibody clone with 65669-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

65669-1-PBS bindet in FC Ly-6C und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Ratte / IgG2a
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: lymphocyte antigen 6 complex, locus C1
• GenBank-Zugangsnummer: BC010764
• Gene symbol: Ly-6C
• Gene ID (NCBI): 17067
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Ly-6C (lymphocyte antigen 6 complex, locus C) is a 14-17 kDa GPI-linked cell surface antigen that belongs to the Ly-6 family of glycosyl phosphatidylinositol-anchored surface glycoproteins (PMID: 9192663). Ly-6C is expressed on mouse monocytes/macrophages, endothelial cells, granulocytes, thymocytes, and some T cell subsets (PMID: 2849552). The two alleles of Ly-6C, Ly-6C.1 and Ly-6C.2, result in differential expression of this protein on subpopulations of CD4+ T cells (PMID: 15057973; 9126982). Ly-6C has been reported as a marker of memory CD8+ T cells (PMID: 7543536).