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MADD Polyklonaler Antikörper

MADD Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29663-1-PBS

Synonyme

MAP kinase-activating death domain protein, KIAA0358, IG20, FLJ36300, FLJ35600

Filter:
  • Western Blot (WB) analysis of various lysates using MADD Polyclonal antibody (29663-1-AP)

    WB analysis using 29663-1-AP (same clone as 29663-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29663-1-AP (MADD antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29663-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human ovary cancer tissue using MADD Polyclonal antibody (29663-1-AP)

    IHC staining of human ovary cancer using 29663-1-AP (same clone as 29663-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 29663-1-AP (MADD antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29663-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

29663-1-PBS bindet in WB, IHC, Indirect ELISA MADD und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MADD fusion protein Ag31292
Vollständiger Name MAP-kinase activating death domain
Berechnetes Molekulargewicht 1544 aa, 171 kDa
Beobachtetes Molekulargewicht200-250 kDa
GenBank-ZugangsnummerBC040484
Gene symbol MADD
Gene ID (NCBI) 8567
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MADD, MAP kinase-activating death domain protein, belongs to the DENN family, which regulates the Rab family is small GTPases (PMID: 20937701, PMID: 18559336). MADD plays a role in synaptic vesicle formation and in vesicle trafficking at the neuromuscular junction. MADD is also involved in TNFA-mediated activation of the MAPK pathway, including ERK1/2 (PMID: 32761064). KIF1Bβ- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through MADD (PMID: 18849981).