TAB2 Rekombinanter Antikörper

TAB2 Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

230118G2

Kat-Nr. : 82948-1-PBS

Synonyme

MAP3K7IP2, 230118G2, KIAA0733, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, TAB 2

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  WB analysis using 82948-1-RR (same clone as 82948-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82948-1-RR (MAP3K7IP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82948-1-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP00082-3

  Cytometric bead array standard curve of MP00082-3, TAB2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 82948-3-PBS. Detection antibody: 82948-1-PBS. Standard: Ag5742. Range: 0.625-20 ng/mL.

• 

  Affinity and Kinetic Characterization of 82948-1-RR

  Biolayer interferometry (BLl) kinetic assays of 82948-1-RR against Human TAB2 were performed. The affinity constant is 0.107 nM.

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Geprüfte Anwendungen

Produktinformation

82948-1-PBS bindet in WB, Cytometric bead array, Indirect ELISA TAB2 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: TAB2 fusion protein Ag5742
• Vollständiger Name: mitogen-activated protein kinase kinase kinase 7 interacting protein 2
• Berechnetes Molekulargewicht: 76 kDa
• Beobachtetes Molekulargewicht: 77 kDa
• GenBank-Zugangsnummer: BC035910
• Gene symbol: MAP3K7IP2
• Gene ID (NCBI): 23118
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tab2 has a role in the inflammatory signal transduction pathway and is involved in the reversal of NCoR-dependent and NFkB- or APP-mediated gene repression and androgen antagonist response. Besides, it is identified as a cofactor for ERBB4 to assemble NCoR corepressor complex in response to neuregulin [PMID:16469706]. It also functions as an adaptor that links TAK1 and TRAF6 in response to interleukin-1β (IL-1β) or tumour necrosis factor-α (TNF-α), and thereby mediates TAK1 activation [PMID:11460167].