TAB2 Rekombinanter Antikörper

TAB2 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

230118G2

Kat-Nr. : 82948-1-RR

Synonyme

MAP3K7IP2, TAB-2, TAB 2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, KIAA0733

---

• 

  WB analysis using 82948-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 82948-1-RR (MAP3K7IP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

• 

  Affinity and Kinetic Characterization of 82948-1-RR

  Biolayer interferometry (BLl) kinetic assays of 82948-1-RR against Human TAB2 were performed. The affinity constant is 0.107 nM.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HepG2-Zellen, HEK-293T-Zellen, L02-Zellen, Raji-Zellen, RAW 264.7-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

82948-1-RR bindet in WB, ELISA TAB2 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: TAB2 fusion protein Ag5742
• Vollständiger Name: mitogen-activated protein kinase kinase kinase 7 interacting protein 2
• Berechnetes Molekulargewicht: 76 kDa
• Beobachtetes Molekulargewicht: 77 kDa
• GenBank-Zugangsnummer: BC035910
• Gene symbol: MAP3K7IP2
• Gene ID (NCBI): 23118
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tab2 has a role in the inflammatory signal transduction pathway and is involved in the reversal of NCoR-dependent and NFkB- or APP-mediated gene repression and androgen antagonist response. Besides, it is identified as a cofactor for ERBB4 to assemble NCoR corepressor complex in response to neuregulin [PMID:16469706]. It also functions as an adaptor that links TAK1 and TRAF6 in response to interleukin-1β (IL-1β) or tumour necrosis factor-α (TNF-α), and thereby mediates TAK1 activation [PMID:11460167].