MASP1 Rekombinanter Antikörper
MASP1 Rekombinant Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
Maus
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
251559F5
Kat-Nr. : 86615-3-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
86615-3-PBS bindet in WB, Indirect ELISA MASP1 und zeigt Reaktivität mit Maus
| Getestete Reaktivität | Maus |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | MASP1 fusion protein Eg4420 |
| Vollständiger Name | mannan-binding lectin serine peptidase 1 |
| Berechnetes Molekulargewicht | 80 kDa |
| Beobachtetes Molekulargewicht | 90 kDa |
| GenBank-Zugangsnummer | NM_008555.2 |
| Gene symbol | Masp1 |
| Gene ID (NCBI) | 17174 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
MASP1, also known as CRARF, is a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties, which leads to activation of the associated proteases MASP1 and MASP2. The observed molecular weight of 90 kDa is consistent with the values described in the literature (PMID: 24472859, 12396007).

