MASP1 Rekombinanter Antikörper

MASP1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251559F5

Kat-Nr. : 86615-3-PBS

Synonyme

Complement factor MASP-3, Complement-activating component of Ra-reactive factor, Crarf, EC:3.4.21.-, Mannan-binding lectin serine protease 1



Geprüfte Anwendungen

Produktinformation

86615-3-PBS bindet in WB, Indirect ELISA MASP1 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen MASP1 fusion protein Eg4420
Vollständiger Name mannan-binding lectin serine peptidase 1
Berechnetes Molekulargewicht80 kDa
Beobachtetes Molekulargewicht 90 kDa
GenBank-ZugangsnummerNM_008555.2
Gene symbol Masp1
Gene ID (NCBI) 17174
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MASP1, also known as CRARF, is a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties, which leads to activation of the associated proteases MASP1 and MASP2. The observed molecular weight of 90 kDa is consistent with the values described in the literature (PMID: 24472859, 12396007).