MASP1 Rekombinanter Antikörper

MASP1 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

251559F5

Kat-Nr. : 86615-3-RR

Synonyme

Complement factor MASP-3, Complement-activating component of Ra-reactive factor, Crarf, EC:3.4.21.-, Mannan-binding lectin serine protease 1

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  WB analysis of mouse serum using 86615-3-RR

  mouse serum were subjected to SDS PAGE followed by western blot with 86615-3-RR (MASP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: mouse serum

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

86615-3-RR bindet in WB, ELISA MASP1 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: MASP1 fusion protein Eg4420
• Vollständiger Name: mannan-binding lectin serine peptidase 1
• Berechnetes Molekulargewicht: 80 kDa
• Beobachtetes Molekulargewicht: 90 kDa
• GenBank-Zugangsnummer: NM_008555.2
• Gene symbol: Masp1
• Gene ID (NCBI): 17174
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MASP1, also known as CRARF, is a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties, which leads to activation of the associated proteases MASP1 and MASP2. The observed molecular weight of 90 kDa is consistent with the values described in the literature (PMID: 24472859, 12396007).