MATN1 Rekombinanter Antikörper

MATN1 Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241643D1

Kat-Nr. : 84313-1-PBS

Synonyme

241643D1, Cartilage matrix protein, CMP, CRTM, Matrilin 1

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  WB analysis of mouse embryo using 84313-1-RR (same clone as 84313-1-PBS)

  mouse embryo tissue were subjected to SDS PAGE followed by western blot with 84313-1-RR (MATN1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84313-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP01215-1

  Cytometric bead array standard curve of MP01215-1, MATN1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84313-2-PBS. Detection antibody: 84313-1-PBS. Standard: Ag29386. Range: 0.313-40 ng/mL.

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  Affinity and Kinetic Characterization of 84313-1-PBS

  Biolayer interferometry (BLl) kinetic assay of 84313-1-PBS against Human MATN1 was performed. The affinity constant is 2.30 nM.

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  Affinity and Kinetic Characterization of 84313-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84313-1-RR against Human MATN1 were performed. The affinity constant is 1.14 nM.

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Geprüfte Anwendungen

Produktinformation

84313-1-PBS bindet in WB, Cytometric bead array, Indirect ELISA MATN1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: MATN1 fusion protein Ag29386
• Vollständiger Name: matrilin 1, cartilage matrix protein
• Berechnetes Molekulargewicht: 54 kDa
• Beobachtetes Molekulargewicht: 54 kDa
• GenBank-Zugangsnummer: NM_002379
• Gene symbol: MATN1
• Gene ID (NCBI): 4146
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MATN1 (matrilin 1), also known as CMP. It is expected to be located in extracellular space, the protein is mainly expressed in cartilage tissue and retina tissue. Also, the protein is a member of von Willebrand factor A domain containing protein family. This family of proteins are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. Mutations of this gene have been associated with variety of inherited chondrodysplasias. It is reproted that COMP and matrilin-1 elute together in the gel filtration of cartilage extracts and can be co-immunoprecipitated with the presence of calcium (PMID: 15075323). The calculated molecular weight of MATN1 is 54 kDa.