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MBD5 Polyklonaler Antikörper

MBD5 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 15961-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse heart tissue using MBD5 Polyclonal antibody (15961-1-AP)

    WB analysis of mouse heart using 15961-1-AP (same clone as 15961-1-PBS)

    mouse heart tissue were subjected to SDS PAGE followed by western blot with 15961-1-AP (MBD5 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15961-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human skeletal muscle tissue using MBD5 Polyclonal antibody (15961-1-AP)

    WB analysis of human skeletal muscle using 15961-1-AP (same clone as 15961-1-PBS)

    human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 15961-1-AP (MBD5 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15961-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse skeletal muscle tissue using MBD5 Polyclonal antibody (15961-1-AP)

    WB analysis of mouse skeletal muscle using 15961-1-AP (same clone as 15961-1-PBS)

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 15961-1-AP (MBD5 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15961-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

15961-1-PBS bindet in WB, Indirect ELISA MBD5 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MBD5 fusion protein Ag8728
Vollständiger Name methyl-CpG binding domain protein 5
Berechnetes Molekulargewicht 292 aa, 31 kDa, 160 kDa
Beobachtetes Molekulargewicht 160 kDa
GenBank-ZugangsnummerBC014534
Gene symbol MBD5
Gene ID (NCBI) 55777
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

In vertebrates, cytosine methylation in DNA is one of the major epigenetic modifications, which regulates many cellular events, including developmental gene expression, X chromosome inactivation, genome defense, and genomic imprinting. DNA methylation exerts regulatory functions by recruiting specific binding proteins that contain a highly conserved methyl-CpG binding domain (MBD) [PMID:12610534,16403636]. Methyl-CpG binding domain protein 5 (MBD5) belongs to the MBD family proteins, which play central roles in transcriptional regulation and development. It is a candidate gene involved in human 2q23.1 microdeletion syndrome [PMID:23077600].