MCCC2 Polyklonaler Antikörper

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• KD/KO Validated

MCCC2 Polyklonal Antikörper für WB, IHC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12117-1-PBS

Synonyme

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  WB analysis of human liver using 12117-1-AP (same clone as 12117-1-PBS)

  human liver tissue were subjected to SDS PAGE followed by western blot with 12117-1-AP (MCCC2 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12117-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse kidney using 12117-1-AP (same clone as 12117-1-PBS)

  IP result of anti-MCCC2 (IP:12117-1-AP, 4ug; Detection:12117-1-AP 1:300) with mouse kidney tissue lysate 4000ug. This data was developed using the same antibody clone with 12117-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas cancer using 12117-1-AP (same clone as 12117-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer using 12117-1-AP (MCCC2 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 12117-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

12117-1-PBS bindet in WB, IHC, IP, Indirect ELISA MCCC2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: MCCC2 fusion protein Ag2767
• Vollständiger Name: methylcrotonoyl-Coenzyme A carboxylase 2 (beta)
• Berechnetes Molekulargewicht: 563 aa, 61 kDa
• Beobachtetes Molekulargewicht: 61 kDa
• GenBank-Zugangsnummer: BC014897
• Gene symbol: MCCC2
• Gene ID (NCBI): 64087
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MCCC2(Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial) is also named as MCCB and belongs to the AccD/PCCB family. The putative 563-amino acid polypeptide has a calculated molecular mass of 61 kD and contains an N-terminal mitochondrial targeting sequence(PMID:11181649). It catalyzes carboxylation of 3 methylcrotonyl COA to form 3 methylglutaconyl-COA and is probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits. Defects in MCCC2 are the cause of methylcrotonoyl-CoA carboxylase 2 deficiency (MCC2D).