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MCOLN1 Polyklonaler Antikörper

MCOLN1 Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 15291-1-PBS

Synonyme

MSTP080, MST080, MLIV, ML4, ML1

Filter:
  • Western Blot (WB) analysis of various lysates using MCOLN1 Polyclonal antibody (15291-1-AP)

    WB analysis using 15291-1-AP (same clone as 15291-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 15291-1-AP (MCOLN1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15291-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using MCOLN1 Polyclonal antibody (15291-1-AP)

    IHC staining of mouse brain using 15291-1-AP (same clone as 15291-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 15291-1-AP (MCOLN1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15291-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using MCOLN1 Polyclonal antibody (15291-1-AP)

    IHC staining of mouse brain using 15291-1-AP (same clone as 15291-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 15291-1-AP (MCOLN1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15291-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using MCOLN1 Polyclonal antibody (15291-1-AP)

    IF Staining of U2OS using 15291-1-AP (same clone as 15291-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed U2OS cells using MCOLN1 antibody (15291-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 15291-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

15291-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA MCOLN1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MCOLN1 fusion protein Ag7493
Vollständiger Name mucolipin 1
Berechnetes Molekulargewicht 65 kDa
Beobachtetes Molekulargewicht60-65 kDa
GenBank-ZugangsnummerBC005149
Gene symbol MCOLN1
Gene ID (NCBI) 57192
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MCOLN1, also named MLIV, ML4, MG-2, and Mucolipidin, belongs to the transient receptor (TC 1.A.4) family, Polycystin subfamily, and MCOLN1 sub-subfamily. It is playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. MCOLN1 may play a major role in Ca2+ transport regulating lysosomal exocytosis. It is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration, and strabismus.