MCOLN1 Rekombinanter Antikörper

MCOLN1 Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242586D4

Kat-Nr. : 85339-1-PBS

Synonyme

242586D4, MG 2, ML1, ML4, MLIV

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  WB analysis of rat kidney using 85339-1-RR (same clone as 85339-1-PBS)

  rat kidney tissue were subjected to SDS PAGE followed by western blot with 85339-1-RR (MCOLN1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85339-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat brain using 85339-1-RR (same clone as 85339-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 85339-1-RR (MCOLN1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85339-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat brain using 85339-1-RR (same clone as 85339-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 85339-1-RR (MCOLN1 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85339-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat kidney using 85339-1-RR (same clone as 85339-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 85339-1-RR (MCOLN1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85339-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

85339-1-PBS bindet in WB, IHC, Indirect ELISA MCOLN1 und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: MCOLN1 fusion protein Ag7493
• Vollständiger Name: mucolipin 1
• Berechnetes Molekulargewicht: 65 kDa
• Beobachtetes Molekulargewicht: 60 kDa
• GenBank-Zugangsnummer: BC005149
• Gene symbol: MCOLN1
• Gene ID (NCBI): 57192
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MCOLN1, also named MLIV, ML4, MG-2, and Mucolipidin, belongs to the transient receptor (TC 1.A.4) family, Polycystin subfamily, and MCOLN1 sub-subfamily. It is playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. MCOLN1 may play a major role in Ca2+ transport regulating lysosomal exocytosis. It is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration, and strabismus.