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MCP-1/CCL2 Polyklonaler Antikörper

MCP-1/CCL2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29547-1-PBS

Synonyme

CCL2, MCP1, MCP-1, chemokine (C C motif) ligand 2, CCL-2

Filter:
  • Western Blot (WB) analysis of THP-1 cells using MCP-1/CCL2 Polyclonal antibody (29547-1-AP)

    WB analysis of THP-1 using 29547-1-AP (same clone as 29547-1-PBS)

    Non-treated, and PMA, LPS and Brefeldin A treated THP-1 cells were subjected to SDS PAGE followed by western blot with 29547-1-AP (MCP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29547-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

29547-1-PBS bindet in WB, Indirect ELISA MCP-1/CCL2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Fusionsprotein
Vollständiger Name chemokine (C-C motif) ligand 2
Berechnetes Molekulargewicht 99 aa, 11 kDa
Beobachtetes Molekulargewicht11 kDa
GenBank-ZugangsnummerBC009716
Gene symbol MCP-1/CCL2
Gene ID (NCBI) 6347
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MCP-1, ( also named as CCL2) is a member of the chemokine family. MCP-1 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. MCP-1 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of MCP-1 is associated with severe acute respiratory syndrome coronavirus 2 infection.