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MCP-1/CCL2 Rekombinanter Antikörper

MCP-1/CCL2 Rekombinant Antikörper für FC (Intra)

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC (Intra)

Konjugation

Unkonjugiert

CloneNo.

230270A7

Kat-Nr. : 98044-1-PBS

Synonyme

CCL2, MCP1, MCP-1, CCL-2, CCL 2

Filter:
  • Flow cytometry (FC) experiment of THP-1 cells using Anti-Human MCP-1/CCL2 Rabbit Recombinant Antibody (98044-1-RR)

    FC experiment of THP-1 using 98044-1-RR (same clone as 98044-1-PBS)

    1x10^6 untreated or PMA, LPS and Brefeldin A treated THP-1 cells were intracellularly stained with 0.5 ug Anti-Human MCP-1 Rabbit Recombinant Antibody (98044-1-RR, Clone: 230270A7) and PE-conjugated Goat Anti-Rabbit IgG. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98044-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98044-1-RR

    Affinity and Kinetic Characterization of 98044-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98044-1-RR against Human MCP-1/CCL2 were performed. The affinity constant is 8.71 nM.

Geprüfte Anwendungen

Produktinformation

98044-1-PBS bindet in FC (Intra) MCP-1/CCL2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Fusionsprotein
Vollständiger Name chemokine (C-C motif) ligand 2
Berechnetes Molekulargewicht 99 aa, 11 kDa
GenBank-ZugangsnummerBC009716
Gene symbol MCP-1/CCL2
Gene ID (NCBI) 6347
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C.

Hintergrundinformationen

Monocyte chemotactic protein 1 (MCP-1; also known as CCL2), is chemotactic for monocyte/macrophage, B-cell, and T-lymphocyte, and belongs to the CC subfamily of chemokines. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis.