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MEF2A Polyklonaler Antikörper

MEF2A Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28819-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using MEF2A Polyclonal antibody (28819-1-AP)

    WB analysis using 28819-1-AP (same clone as 28819-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28819-1-AP (MEF2A antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28819-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of rat brain tissue using MEF2A Polyclonal antibody (28819-1-AP)

    IHC staining of rat brain using 28819-1-AP (same clone as 28819-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 28819-1-AP (MEF2A antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28819-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of rat brain tissue using MEF2A Polyclonal antibody (28819-1-AP)

    IHC staining of rat brain using 28819-1-AP (same clone as 28819-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 28819-1-AP (MEF2A antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28819-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

28819-1-PBS bindet in WB, IHC, Indirect ELISA MEF2A und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MEF2A fusion protein Ag30349
Vollständiger Name myocyte enhancer factor 2A
Berechnetes Molekulargewicht 499 aa, 54 kDa
Beobachtetes Molekulargewicht50-70kDa
GenBank-ZugangsnummerBC013437
Gene symbol MEF2A
Gene ID (NCBI) 4205
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MEF2A belongs to a family of DNA binding regulatory proteins. Each of these proteins which belong to the myocyte-specific enhancer factor-2 (MEF2) family binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. MEF2A plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. MEF2A also has key roles in cardiac and skeletal muscle development. MEF2A is especially abundant in granule neurons of the cerebellar cortex throughout the period of synaptogenesis. This antibody can detect two bands around 60 kDa to 70 kDa, the larger band may correspond to its post-translational modifications.(PMID: 15483225,16484498, 23486945 )