MEK6 Polyklonaler Antikörper

MEK6 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 51094-1-PBS

Synonyme

MAP2K6, MKK6, Dual specificity mitogen-activated protein kinase kinase 6, EC:2.7.12.2, MAP kinase kinase 6

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  WB analysis of HEK-293 using 51094-1-AP (same clone as 51094-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 51094-1-AP (MEK6 antibody at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51094-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

51094-1-PBS bindet in WB, Indirect ELISA MEK6 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: mitogen-activated protein kinase kinase 6
• Berechnetes Molekulargewicht: 334 aa, 37 kDa
• Beobachtetes Molekulargewicht: 36 kDa
• GenBank-Zugangsnummer: BC012009
• Gene symbol: MEK6
• Gene ID (NCBI): 5608
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MAPKK6 (Dual specificity mitogen activated protein kinase kinase 6), also known as MAP2K6 / MEK6 / MKK6, is a member of MAPKK protein kinase family. MKK6 plays an important role in intracellular signaling pathways leading toward activation of the p38 MAP kinase. MEK6 phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. MEK6 plays a complex role in cancer, with some evidence showing it can promote tumor growth. Overexpression of MEK6 has been linked to decreased survival in lung adenocarcinoma, breast cancer, and melanoma.