MEN1 Monoklonaler Antikörper

MEN1 Monoklonal Antikörper für WB, IHC, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, IHC, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3A6A11

Kat-Nr. : 68473-1-PBS

Synonyme

3A6A11, MEAI, Menin, Menin 1, SCG2

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  WB analysis using 68473-1-Ig (same clone as 68473-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68473-1-Ig (MEN1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68473-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 68473-1-Ig (same clone as 68473-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 68473-1-Ig (MEN1 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68473-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 68473-1-Ig (same clone as 68473-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 68473-1-Ig (MEN1 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68473-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP50886-1

  Cytometric bead array standard curve of MP50886-1, MEN1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68473-2-PBS. Detection antibody: 68473-1-PBS. Standard:Ag7566. Range: 1.563-200 ng/mL.

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  Cytometric bead array standard curve of MP50886-2

  Cytometric bead array standard curve of MP50886-2, MEN1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68473-1-PBS. Detection antibody: 68473-3-PBS. Standard:Ag7566. Range: 3.125-200 ng/mL.

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Geprüfte Anwendungen

Produktinformation

68473-1-PBS bindet in WB, IHC, Cytometric bead array, Indirect ELISA MEN1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: MEN1 fusion protein Ag7566
• Vollständiger Name: multiple endocrine neoplasia I
• Berechnetes Molekulargewicht: 68 kDa
• Beobachtetes Molekulargewicht: 68-70 kDa
• GenBank-Zugangsnummer: BC002544
• Gene symbol: MEN1
• Gene ID (NCBI): 4221
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MEN1, also named as Menin or MEAI, is a tumor suppressor protein encoded by the MEN1 gene. It is located in nucleus and ubiquitous expression in spleen and lymph node. The calculated molecular weight of MEN1 is 68 kDa. Its inactivation has been implicated in tumors of many endocrine tissues. Germline inactivating mutations of MEN1 gene are the main cause of multiple endocrine neoplasia type 1 (MEN1), a syndrome characterized by tumors in the pituitary gland, the parathyroid glands, and the enteropancreatic neuroendocrine tissues. Recent study shows astroglia menin deficiency leads to depressive-like behaviors in mice.