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METTL1 Monoklonaler Antikörper

METTL1 Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

Hausschwein, human, Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

2C3G7

Kat-Nr. : 68501-1-PBS

Synonyme

C12orf1, FLJ95748, methyltransferase like 1, METTL1, TRM8, tRNA(m7G46) methyltransferase, YDL201w

Filter:
  • Western Blot (WB) analysis of various lysates using METTL1 Monoclonal antibody (68501-1-Ig)

    WB analysis using 68501-1-Ig (same clone as 68501-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68501-1-Ig (METTL1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68501-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using METTL1 Monoclonal antibody (68501-1-Ig)

    WB analysis using 68501-1-Ig (same clone as 68501-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68501-1-Ig (METTL1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68501-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68501-1-PBS bindet in WB, ELISA METTL1 und zeigt Reaktivität mit Hausschwein, human, Maus

Getestete Reaktivität Hausschwein, human, Maus
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen METTL1 fusion protein Ag7055
Vollständiger Name methyltransferase like 1
Berechnetes Molekulargewicht 31 kDa
Beobachtetes Molekulargewicht31 kDa
GenBank-ZugangsnummerBC000550
Gene symbol METTL1
Gene ID (NCBI) 4234
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

METTL1 methyltransferase mediates m7G methylation within miRNAs and regulates cell migration via its catalytic activity. METTL1 can be inactivated by phosphorylation at Ser27 by protein kinase B (PKBα). Overexpression of METTL1 is widely observed among human cancers. It is also crucial for the regulation of chemoresistance in cancer treatment. In addition, mutations in the human N7-methylguanosine (m7G) methyltransferase complex METTL1/WDR4 cause primordial dwarfism and brain malformation.