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METTL13 Polyklonaler Antikörper

METTL13 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24379-1-PBS

Synonyme

CGI 01, EEF1AKNMT, FEAT, KIAA0859, methyltransferase like 13

Filter:
  • Western Blot (WB) analysis of various lysates using METTL13 Polyclonal antibody (24379-1-AP)

    WB analysis using 24379-1-AP (same clone as 24379-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 24379-1-AP (METTL13 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24379-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U-251 cells using METTL13 Polyclonal antibody (24379-1-AP)

    IF Staining of U-251 using 24379-1-AP (same clone as 24379-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed U-251 cells using METTL13 antibody (24379-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 24379-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

24379-1-PBS bindet in WB, IF/ICC, Indirect ELISA METTL13 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen METTL13 fusion protein Ag19355
Vollständiger Name methyltransferase like 13
Berechnetes Molekulargewicht 699 aa, 79 kDa
Beobachtetes Molekulargewicht72-78 kDa
GenBank-ZugangsnummerBC029083
Gene symbol METTL13
Gene ID (NCBI) 51603
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Protein methyltransferase like 13 (METTL13), also called FEAT, is coded by gene METTL13, which is located at chromosome 1q24.3. Purified from rat livers in 2011 by a Japanese researcher, METTL13 was found to be abnormally overexpressed in several human cancers including lung cancer and to drive tumorigenesis in transgenic mice. A study indicated that METTL13 inhibits apoptosis of lung, breast and liver cancer cells and miR-16 can repress the expression of METTL13 by binding to its 3′-untranslated region. (PMID: 33985542)