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MEX3A Polyklonaler Antikörper

MEX3A Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30865-1-PBS

Synonyme

RKHD4, MEX 3A

Filter:
  • Western Blot (WB) analysis of various lysates using MEX3A Polyclonal antibody (30865-1-AP)

    WB analysis using 30865-1-AP (same clone as 30865-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30865-1-AP (MEX3A antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30865-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of SH-SY5Y cells using MEX3A Polyclonal antibody (30865-1-AP)

    IF Staining of SH-SY5Y using 30865-1-AP (same clone as 30865-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using MEX3A antibody (30865-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 30865-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30865-1-PBS bindet in WB, IF/ICC, Indirect ELISA MEX3A und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MEX3A fusion protein Ag33619
Vollständiger Name mex-3 homolog A (C. elegans)
Berechnetes Molekulargewicht54 kDa
Beobachtetes Molekulargewicht65-70 kDa
GenBank-ZugangsnummerNM_001093725
Gene symbol MEX3A
Gene ID (NCBI) 92312
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MEX3A is a member of the MEX3 family, which widely exists in mammalian cells and encodes four different genes, MEX3A, MEX3B, MEX3C, and MEX3D. The MEX3 protein of mammals is composed of two RNA-binding KH domains and a ring domain with E3 ubiquitin ligase activity at the C terminal. The ring finger domain endows human MEX3 protein the ability to regulate ubiquitination of target proteins and then influencing their protein stability and subcellular localization.MEX3A plays complex and diverse roles in the development of various cancers. MEX3A plays a pivotal role in the post-transcriptional procession of mRNA and gene expression. MEX3A gene expression may be closely connected with malignant tumor development and progression. In most literature, MEX3A detects molecular weights between 60 and 70kDa (PMID:33159833,37845346,36354374,35490173,34976441,33159833)