MGL2 Rekombinanter Antikörper

MGL2 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242983C6

Kat-Nr. : 85876-1-PBS

Synonyme

Macrophage galactose N-acetyl-galactosamine specific lectin 2 , Macrophage galactose-type C-type lectin 2

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  WB analysis using 85876-1-RR (same clone as 85876-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85876-1-RR (Mgl2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85876-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 85876-1-RR (same clone as 85876-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85876-1-RR (Mgl2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85876-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

85876-1-PBS bindet in WB, Indirect ELISA MGL2 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: MGL2 fusion protein Eg2727
• Vollständiger Name: macrophage galactose N-acetyl-galactosamine specific lectin 2
• Berechnetes Molekulargewicht: 38 kDa
• Beobachtetes Molekulargewicht: 40 kDa
• GenBank-Zugangsnummer: NM_145137.2
• Gene symbol: Mgl2
• Gene ID (NCBI): 216864
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MGL2 is mainly expressed on immature dendritic cell (DCs) , tolerogenic DCs, type 2 DCs, and alternatively activated macrophages. MGL2 protein has carbohydrate-binding activity, specifically recognizing and binding to terminal GalNAc (n-acetyl 2-amino-2-deoxy-D-galactopyranose) residues, including the TN antigen (Galnac- αthrser) . This specific binding makes it play an important role in the recognition and processing of glycosylated pathogens, apoptotic cell fragments and tumor cells.