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MGST3 Polyklonaler Antikörper

MGST3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20114-1-PBS

Synonyme

EC:1.11.1.-, EC:2.5.1.-, EC:4.4.1.20, Glutathione peroxidase MGST3, Glutathione S-transferase 3, mitochondrial

Filter:
  • Western Blot (WB) analysis of various lysates using MGST3 Polyclonal antibody (20114-1-AP)

    WB analysis using 20114-1-AP (same clone as 20114-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20114-1-AP (MGST3 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20114-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

20114-1-PBS bindet in WB, Indirect ELISA MGST3 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MGST3 fusion protein Ag13932
Vollständiger Name microsomal glutathione S-transferase 3
Berechnetes Molekulargewicht 152 aa, 17 kDa
Beobachtetes Molekulargewicht16 kDa
GenBank-ZugangsnummerBC000505
Gene symbol MGST3
Gene ID (NCBI) 4259
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Microsomal glutathione transferase 3 (MGST3) is member of microsomal prostaglandin E synthases super family that exhibits diversified functions in eicosanoid and GSH metabolism. MGST3 expression level correlates with hippocampal size, and mutation of MGST3 contributes to spinal muscular dystrophy (PMID: 37760932). MGST3 KD did not alter intracellular reactive oxygen species level but selectively reduced the expression of apoptosis indicators which could be associated with the receptor of cysteinyl leukotrienes, the downstream metabolites of MGST3 in arachidonic acid pathway (PMID: 38971310).