CTAGE5 Polyklonaler Antikörper

CTAGE5 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31986-1-AP

Synonyme

cTAGE family member 5, CTAGE family member 5 ER export factor, CTAGE family, member 5, Cutaneous T-cell lymphoma-associated antigen 5, MEA11

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  WB analysis using 31986-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31986-1-AP (CTAGE5 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HepG2-Zellen, HuH-7-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:5000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

31986-1-AP bindet in WB, ELISA CTAGE5 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CTAGE5 fusion protein Ag34060
• Vollständiger Name: CTAGE family, member 5
• Berechnetes Molekulargewicht: 160 kDa
• Beobachtetes Molekulargewicht: 240 kDa
• GenBank-Zugangsnummer: BC130537
• Gene symbol: CTAGE5
• Gene ID (NCBI): 4253
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cutaneous T-cell lymphoma-associated antigen 5 (CTAGE5, also known as MIA2) is a protein involved in the regulation of intracellular transport and secretion. It plays a crucial role in the trafficking of large cargo proteins, such as collagen VII, from the endoplasmic reticulum (ER) to the Golgi apparatus (PMID: 25202031; 27170179). CTAGE5 forms a complex with TANGO1, another cargo receptor, to facilitate the export of collagen VII from the ER (PMID: 21525241). This process is essential for the proper secretion of collagen and other large proteins, which are critical for maintaining tissue integrity and function. Additionally, CTAGE5 produces 240 and 120 kDa protein isoforms (PMID: 21807889).