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MIER3 Polyklonaler Antikörper

MIER3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17543-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse uterus tissue using MIER3 Polyclonal antibody (17543-1-AP)

    WB analysis of mouse uterus using 17543-1-AP (same clone as 17543-1-PBS)

    mouse uterus tissue were subjected to SDS PAGE followed by western blot with 17543-1-AP (MIER3 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17543-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse uterus tissue using MIER3 Polyclonal antibody (17543-1-AP)

    WB analysis of mouse uterus using 17543-1-AP (same clone as 17543-1-PBS)

    mouse uterus tissue were subjected to SDS PAGE followed by western blot with 17543-1-AP (MIER3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17543-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17543-1-PBS bindet in WB, Indirect ELISA MIER3 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MIER3 fusion protein Ag11604
Vollständiger Name mesoderm induction early response 1, family member 3
Berechnetes Molekulargewicht 522 aa, 59 kDa
Beobachtetes Molekulargewicht 55 kDa
GenBank-ZugangsnummerBC041348
Gene symbol MIER3
Gene ID (NCBI) 166968
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The mesoderm induction early response (MIER) protein family is known as fibroblast growth factor (FGF)-regulated immediate-early protein family. Activated by FGF, MIER proteins may have a pivotal role in FGF-regulated cellular activities, indicating a potential influence in the progression of certain cancers [PMID:15117948]. MIER3 localizes to the nucleus and primarily functions as a transcriptional repressor. Rat mammary carcinoma susceptibility 1b (Mcs1b) is a quantitative trait locus on RN02 that confers decreased susceptibility when Copenhagen (COP)-resistant alleles are introgressed into a Wistar Furth (WF)-susceptible genome. MIER3 is a candidate Mcs1b gene [PMID:22993404].