MINDY3 Polyklonaler Antikörper

MINDY3 Polyklonal Antikörper für IP, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IP, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 26478-1-AP

Synonyme

C10orf97, CARP, Dermal papilla-derived protein 5, DERP5, Deubiquitinating enzyme MINDY-3

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  IP experiment of HCT 116 using 26478-1-AP

  IP result of anti-C10orf97 (IP:26478-1-AP, 4ug; Detection:26478-1-AP 1:1000) with HCT 116 cells lysate 1920 ug.

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Geprüfte Anwendungen

• Erfolgreiche IP: HCT 116-Zellen

Empfohlene Verdünnung

• Immunpräzipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

26478-1-AP bindet in IP, ELISA MINDY3 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: MINDY3 fusion protein Ag23520
• Vollständiger Name: chromosome 10 open reading frame 97
• Beobachtetes Molekulargewicht: 49 kDa
• GenBank-Zugangsnummer: BC067799
• Gene symbol: C10orf97
• Gene ID (NCBI): 80013
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MINDY3 (also known as FAM63B) is a deubiquitinating enzyme (DUB) localized to the endoplasmic reticulum and belongs to the MINDY family. This protein specifically recognizes and cleaves lysine 48 (K48)-linked ubiquitin chains, which serve as the primary signal targeting proteins for proteasomal degradation, thereby playing a critical role in regulating protein stability. Research indicates that MINDY3 influences various cellular processes through its deubiquitination activity, including endoplasmic reticulum-associated degradation (ERAD), cellular stress response, and cell cycle regulation. Dysregulation of its function is closely associated with pathological processes such as cancer and neurodegenerative diseases, making it a potential target for therapeutic research.