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MINDY3 Polyklonaler Antikörper

MINDY3 Polyklonal Antikörper für IP, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IP, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 26478-1-PBS

Synonyme

C10orf97, CARP, Dermal papilla-derived protein 5, DERP5, Deubiquitinating enzyme MINDY-3

Filter:
  • Immunoprecipitation (IP) experiment of HCT 116 cells using MINDY3 Polyclonal antibody (26478-1-AP)

    IP experiment of HCT 116 using 26478-1-AP (same clone as 26478-1-PBS)

    IP result of anti-C10orf97 (IP:26478-1-AP, 4ug; Detection:26478-1-AP 1:1000) with HCT 116 cells lysate 1920 ug. This data was developed using the same antibody clone with 26478-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

26478-1-PBS bindet in IP, ELISA MINDY3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MINDY3 fusion protein Ag23520
Vollständiger Name chromosome 10 open reading frame 97
Beobachtetes Molekulargewicht49 kDa
GenBank-ZugangsnummerBC067799
Gene symbol C10orf97
Gene ID (NCBI) 80013
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MINDY3 (also known as FAM63B) is a deubiquitinating enzyme (DUB) localized to the endoplasmic reticulum and belongs to the MINDY family. This protein specifically recognizes and cleaves lysine 48 (K48)-linked ubiquitin chains, which serve as the primary signal targeting proteins for proteasomal degradation, thereby playing a critical role in regulating protein stability. Research indicates that MINDY3 influences various cellular processes through its deubiquitination activity, including endoplasmic reticulum-associated degradation (ERAD), cellular stress response, and cell cycle regulation. Dysregulation of its function is closely associated with pathological processes such as cancer and neurodegenerative diseases, making it a potential target for therapeutic research.