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MLXIP Monoklonaler Antikörper

MLXIP Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2E11A4

Kat-Nr. : 68977-1-PBS

Synonyme

MLX interacting protein, MIR, KIAA0867, Class E basic helix-loop-helix protein 36, BHLHE36

Filter:
  • Western Blot (WB) analysis of various lysates using MLXIP Monoclonal antibody (68977-1-Ig)

    WB analysis using 68977-1-Ig (same clone as 68977-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68977-1-Ig (MLXIP antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68977-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68977-1-PBS bindet in WB, Indirect ELISA MLXIP und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen MLXIP fusion protein Ag4519
Vollständiger Name MLX interacting protein
Berechnetes Molekulargewicht 919 aa, 100 kDa
Beobachtetes Molekulargewicht 130 kDa
GenBank-ZugangsnummerBC039704
Gene symbol MLXIP
Gene ID (NCBI) 22877
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP. A prominent and specific MLXIP of approximately 130 kDa was detected. It demonstrates that MLXIP associated specifically with Mlx in the cytoplasm (PMID: 11073985).