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MMS2 Rekombinanter Antikörper

MMS2 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251485F12

Kat-Nr. : 86551-3-PBS

Synonyme

UBE2V2, DDVit 1, DDVIT1, EDAF 1, EDAF-1

Filter:
  • Western Blot (WB) analysis of various lysates using MMS2 Recombinant antibody (86551-3-RR)

    WB analysis using 86551-3-RR (same clone as 86551-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86551-3-RR (MMS2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86551-3-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86551-3-PBS bindet in WB, Indirect ELISA MMS2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen MMS2 fusion protein Ag1111
Vollständiger Name ubiquitin-conjugating enzyme E2 variant 2
Berechnetes Molekulargewicht 16 kDa
Beobachtetes Molekulargewicht 16-18 kDa
GenBank-ZugangsnummerBC007051
Gene symbol MMS2
Gene ID (NCBI) 7336
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MMS2 encodes a 137-amino acid, 15.2-kDa protein with significant sequence homology to a conserved family of ubiquitin-conjugating (Ubc) proteins (PMID: 9576943). Mms2 is a ubiquitin E2-variant protein with a very well-documented function in the tolerance pathway that protects both human and yeast cells from the lethal and mutagenic effects of DNA damage (PMID: 36934633). A high expression level of human MMS2 is associated with poor survival prognosis in different cancer diseases (PMID: 36934633).